In this episode for Mental Health Awareness Month, UR School of Medicine and Dentistry explores the emotional toll of high-pressure careers in science and medicine, and why acknowledging our limits is essential to thriving. Amber Rivera, Director of Learner Life and Wellness here at SMD, shares how she supports graduate students and postdocs through moments of stress, uncertainty, and overwhelm. Karen Leitner, MD alum and now a leadership and wellness coach for women physicians, reflects on her personal experience with burnout and how she redefined success after stepping away from clinical practice. Together, they discuss a culture of perfectionism, the importance of self-compassion, and the mindset shifts that can help us show up fully for our careers and for ourselves.